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”The entourage effect is the term used to describe enhancement of efficacy, with related improvement in overall therapeutic effectiveness, derived from combining phytocannabinoids and other plant-derived molecules.”

U.S. National Institutes of Health's National Library of MedicineThe "Entourage Effect"

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“The synergistic contributions of cannabidiol to Cannabis pharmacology—and specifically analgesia—have been scientifically demonstrated.”

U.S. National Institutes of Health's National Library of MedicineCBD For Pain

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“Ongoing studies show that [the terpene] β-caryophyllene is effective at reducing neuropathic pain in a CB2 receptor-dependent manner.”

U.S. National Institutes of Health's National Library of MedicineTerpenes - b-Caryophyllene

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“Putting these pharmacologic, clinical, and societal issues together, the direction for the future resides in the development of orally administered, highly bioavailable, non-psychoactive phytocannabinoid products that also take advantage of the entourage effect, to provide the millions of people living with debilitating pain a comparatively safe and effective form of relief.”

U.S. National Institutes of Health's National Library of MedicineThe "Entourage Effect"