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3 Cannabinoids To Consider For Your Health

By | Cannabinoids, CBD, Endocannabinoid System | No Comments

3 Cannabinoids To Consider For Your Health

When it comes to cannabinoids, many people are familiar with the two most commonly known molecules, THC and CBD (and their respective variants).

CannabinoidsWhat many people don’t know however is that these molecules have many counterparts within the hemp and cannabis plant genealogy.

There are currently a minimum of 113 known cannabinoids that have been identified through research and independent studies.

Research has revealed that the human endocannabinoid system (ECS) regulates homeostasis within the human body and these plant based molecules (phyto-cannabinoids) interact with the ECS and endogenous cannabinoids to deliver the myriad health benefits that have been reported by users and confirmed in numerous studies.


Below you will find a brief summary of 3 cannabinoids getting more attention recently for their potential holistic properties and health benefits.

CBN – Cannabinol

Cannabinol, or CBN may sound very similar to it’s relative Cannabidiol (CBD) but CBN displays its own unique array of medical benefits and effects that have researchers anxious to continue investigating this molecule.

Some of the benefits already discovered include:

  • Pain relief [1]
  • Anti-insomnia [2]
  • Promotes growth of bone cells
  • Antibacterial [3]
  • Anti-inflammatory [4]
  • Anti-convulsive
  • Appetite stimulant [5]

One of CBN’s most interesting and noteworthy attributes is the sedative effect it has on users. According to a study by Steep Hill Labs, 5mg of CBN is as effective as a 10mg dose of the pharmaceutical sedative diazepam.

CBN does not induce a psychoactive effect and has shown no negative side effects.

CBC – Cannabichromene

Cannabichromene is another lesser known cannabinoid that has some amazing potential medical benefits for users.

Recent studies have suggested that CBC may contribute to the overall analgesic effects of medical cannabis.

Here of some of the most noteworthy findings so far about CBC:

  • Promotes Neurogenesis (Brain Growth) [6]
  • Antidepressant [7]
  • Anti-inflammatory [8]
  • Pain relief [9]
  • Antibacterial and antifungal [10]

CBC has been found to interact with many receptors in the brain. While it is common for most cannabinoids to interact with the CB1 and CB2 receptors, CBD interacts with other receptors as well.

CBC in particular is known to interact with the TRPV1 and TRPA1 receptors as well, which may result in some of its medicinal properties.[6]

CBG – Cannabigerol

CBG is a cannabinoid that is known as the building block for many compounds in cannabis, including THC and CBD.

CBG is non-psychoactive and can be thought of as the “stem cell” or “parent” of other cannabinoids. However, CBG is not found in high concentrations in most strains. Certain strains of hemp may have higher CBG content.

CBG is important because of its numerous health benefits, especially for people with disorders affecting the central nervous system, including neurological diseases, skin disorders, chronic pain, and others.

The medical benefits of CBG are still under investigation, but the list thus far is impressive and growing.

  • Stimulates bone formation and healing [11]
  • Slows tumor growth [12]
  • Antifungal and antibacterial treatment. [13]
  • Relieves pain [14]
  • Reduces inflammation [15]
  • Overactive bladder treatment  [16]
  • Psoriasis and skin treatment.  [17]
  • Glaucoma treatment. [18]
  • Depression and anxiety treatment [19]
  • Neuroprotective effects. [20]

CBG can also affect the body by increasing anandamide levels. Anandamide is a naturally-occurring cannabinoid that helps regulate many biological functions, including appetite, sleep and memory.

The effect of CBG on GABA (gamma aminobutyric acid – a brain chemical that regulates the activity of neurons) uptake was found to be greater than both THC and CBD in one study.

CBG has been shown to block serotonin receptors as well, which suggests a role for CBG in treating depression.

It’s important to note that much of the evidence comes from pre-clinical studies, meaning that the safety and efficacy of most cannabinoids has yet to be proven in humans. That being said, studies on CBN, CBC and CBG have revealed a wide range of possible benefits.

HealthSmart CBD offers full-spectrum hemp oil CBD products that include all three of the amazing cannabinoids and a more comprehensive array of medical cannabinoids than you can find anywhere in any other product.

Study: CBD Reduces Cigarette Consumption By 40%

By | CBD, CBD Research, CBD Vape, Vaporization | No Comments

New study finds CBD can reduce cigarette consumption in tobacco users by 40% in just one week of treatment.

If you are a smoker you have surely heard the all of the statistics by now, but just in case you need a reminder – here are some staggering numbers to consider…

  • Cigarette smoke contains over 4,000 chemicals, including more than 250 known to harm humans.
  • Smoking cigarettes kill more people each year than HIV, illegal drug use, alcohol use, motor vehicle accidents and gun-related incidents combined.
  • 1 out of every 5 deaths in the US is from tobacco.
  • One  person dies every six seconds from tobacco. (That’s 10 People per minute).

Despite the alarming statistics many people find it difficult or impossible to quit tobacco because of an addiction to nicotine.

This is a common condition as nicotine is one of the most addictive substances on the planet and quitting can be a physically and mentally challenging battle for many smokers.

Smoking Vs. Vaping

A lot of ex-smokers have quit smoking cigarettes recently with the advent of vaporizer technology allowing them to avoid the dangers of burning tobacco without completely quitting nicotine.

Unfortunately, these vape pens and devices typically contain “e-juice” that includes nicotine, often in even greater amounts than cigarettes.

On top of the nicotine issue, the vaporizers that create the large clouds of smoke that some users enjoy, also raise a lot of potential risks and health concerns of their own.

It will be years before there is enough definitive evidence to know if vaping nicotine is actually safer or healthier than smoking cigarettes, but it is definitely more convenient and discreet for many users.

Recently, an exciting new alternative has shown tremendous potential to help smokers who want to quit using tobacco and nicotine altogether.

Study: Cannabis Compound Reduces Cigarette Consumption

The scientific journal Addictive Behaviors recently published clinical trial data containing preliminary results showing that inhalation of the non-psychoactive cannabinoid CBD (cannabidiol) significantly mitigates tobacco smokers’ desire for cigarettes.

In the study, 24 cigarette smokers were recruited and split into two groups, receiving inhalers containing CBD or placebo.

Both groups were told to use the inhalers whenever they felt the urge to smoke during a one week period.

Researchers found: “Over the treatment week, placebo treated smokers showed no differences in number of cigarettes smoked. In contrast, those treated with CBD significantly reduced the number of cigarettes smoked by [the equivalent of] 40 percent during treatment.”

Moreover, participants who used CBD did not report experiencing increased cravings for nicotine during the study’s duration.

“This is the first study, as far as we are aware, to demonstrate the impact of CBD on cigarette smoking. These preliminary data, combined with the strong preclinical rationale for use of this compound, suggest CBD to be a potential treatment for nicotine addiction that warrants further exploration.”

The Most Effective Way To Consume CBD

Most people are unaware that the method by which you choose to ingest CBD can dramatically affect the effective dosage you receive.

In general, only a certain percentage of the cannabidiol you consume will be able to enter your system to produce it’s active effects. This is commonly referred to as “bioavailability”.

When consumed orally, the typical bioavailability of CBD is roughly 15 percent of the total milligrams consumed.

Because CBD is hydrophobic, meaning that it is not very water-soluble, it does not like to stay in the bloodstream, accumulating in fatty tissues instead. This reduces bioavailability.

The digestive process known as “first-pass effect” also reduces the concentration of bioactive compounds that can enter the bloodstream after passing through your liver.

The most effective way to offset this loss of bioavailability is to avoid the first-pass effect completely and ingest CBD through vaporization.

When inhaling CBD from a vaporizer cartridge or CBD vape pen, the substance enters through your lungs and diffuses into your your bloodstream directly, bypassing the liver and gut.

This increases amount of CBD in your bloodstream by roughly 400% versus oral consumption to achieve maximum bioavailability of up to 60% of the dosage you consume. This means you can achieve the same beneficial effects with a much smaller amount of cannabidiol.

In addition to the increased bioavailability, vaporization also delivers a much faster onset of effects since it does not have to travel through your digestive system. When vaporizing CBD, the effects can become active within a matter of seconds, compared with typical 30 to 60 minute onset when consumed orally.

When considering all of these factors, vaporization is clearly the most efficient and cost effective way to consume CBD. When used on a regular basis to mitigate the cravings associated with nicotine addiction, research indicates CBD inhalation offers promising potential for helping people to quit smoking tobacco.

A Healthy CBD Vape Alternative

HealthSmart CBD offers a line of CBD vape pens and disposable CBD vape cartridges that contain 100% organic ingredients. Without any additives or fillers commonly found in e-juice or vape products like PG (propylene glycol), PEG (polyethylene glycol), VG (vegetable glycerin) or MCT oil, these CBD products are a more health conscious alternative to other means of vaporization. HealthSmart CBD Vape Cartridges contain only CBD concentrate and natural terpenes.

Click here to Shop HealthSmart CBD Vape Cartridges now available in 3 varieties: Awake, Calm and Relax.

 

References:

https://www.ncbi.nlm.nih.gov/pubmed/23685330

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444130/

https://www.cdc.gov/tobacco/data_statistics/fact_sheets/health_effects/effects_cig_smoking/

FDA Declares CBD ‘Beneficial,’ Wants Your Input ASAP

By | Cannabis Laws, CBD, CBD Oil, PolItics | No Comments

FDA Declares CBD ‘Beneficial,’ Wants Your Input ASAP

The United Nations is trying to figure out how to categorize cannabidiol(CBD), a non-psychoactive and medically beneficial cannabinoid contained in cannabis. And UN officials, through the US Food and Drug Administration (FDA), are asking for your help.

The FDA declared that ‘CBD has been shown to be beneficial.’ Now the agency needs your comments to back it up.

FDA officials put out a call for comments in this morning’s Federal Register, seeking information about CBD and how the UN’s World Health Organization (WHO) should designate it under the 1971 Convention on Psychotropic Substances. In doing so, the FDA acknowledged the ‘beneficial’ effects CBD has shown in patients with neurological disorders.

All those who have information on, or experience with, the use of CBD as a healing substance are encouraged to comment at this federal website. Sept. 13 is the deadline for public comment, and no input will be considered after that date.

 

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